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Studies have found that NNMT expression gradually rises during adipocyte differentiation, and its enhanced activity promotes the differentiation of preadipocytes into mature adipocytes by depleting NAD⁺ and inhibiting the SIRT1 longevity pathway

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Linear relationships were observed between AUC 0–t and BPC157 doses, as well as between C max and BPC157 doses (Figures 1D,E)