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The intrinsic pathway is controlled by the BCL2 protein family, which regulates apoptosis sensitivity through the control of mitochondrial membrane permeability and subsequent release of mitochondrial proteins, such as CYCS (cytochrome C, somatic) and DIABLO/SMAC (diablo IAP-binding mitochondrial protein) [99]

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doi: 10.1080/07315724.2003.10719272 95