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In genetic forms of PD, mutations in genes such as PINK1 , PARKIN , DJ-1 , and LRRK2 further highlight the vulnerability of mitochondrial and proteostatic systems, offering potential therapeutic targets [7, 13, 14]

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132 Generally, Lp(a) levels below 75 nmol/L are considered low risk, levels between 75 and 125 nmol/L are intermediate risk, and levels above 125 nmol/L are high risk