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Screen for what you would screen for with any incretin therapy — personal or family history of medullary thyroid carcinoma or MEN2, pancreatitis history, gallbladder disease, gastroparesis, and pregnancy status

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Similar trends were observed in a mouse model of pancreatic ductal adenocarcinoma (PDAC) ( LSL-Kras G12D/+ Trp53 f/f Pdx1 cre (KP –/– C) mice 28 ) and in humans with renal cell carcinoma 29 (Extended Data Fig