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[5] 6-Phosphogluconate + NADP + → Ribulose 5-phosphate + NADPH + CO 2 Catalytic mechanism of 6-phosphogluconate dehydrogenase The catalytic mechanism of 6-phosphogluconate dehydrogenase closely resembles that of isocitrate dehydrogenase (EC 1.1.1.41), a key enzyme of the citric acid cycle
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