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Senescent cells, despite their pro-inflammatory SASP, also suppress tumor progression in some contexts through 'senescence surveillance'—nearby immune cells recognize and destroy newly senescent cells, including pre-malignant cells undergoing oncogene-induced senescence
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The arguments are its particular combination, such as antidepressant effect (Porsolt’s test, open field) [65] and region-specific influences on brain serotonin synthesis in rats given a particular increase in the substantia nigra [67] vs
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