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After induction, the rats received treatment with PFAgNPs for 14 days: 25 mg/kg, 50 mg/kg, and 100 mg/kg of PFAgNPs, Standard drug control 10 mg/kg Ulipristal acetate, Positive/disease control: 600 mg/kg MSG without any treatment, Normal control

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This ‘cathartic effect’ causes the bowels to empty rapidly and urgently, often resulting in the classic clinical presentation of melena