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Typically, injections are administered once or twice a week

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Pre-osteoblastic cell lines with MC3T3-E1 as a prominent example, offer a more uniform and stable population of immortalized cells suitable for studies of bone tissue engineering ( Although not as prominently as in the case of primary stem cells, pre-osteoblastic cell lines such as MC3T3 and NH3T3 possess a certain degree of osteogenic capacity which can be regulated by the redox environment