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Beside generation of ROS, cyclophosphamide inhibits the endogenous antioxidant pathways, in particular nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway, a master transcription factor for conserving redox homeostasis [19]

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10.1111/cns.13035 3 AhnC.-H.MyongJ

It also has an antioxidant effect‚ which encourages healthy aging