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Genes for sterol regulatory element-binding proteins (SREBPs), the master regulators of de novo lipogenesis ( Srebf1 ) and cholesterol biosynthesis ( Srebf2 ) 35 , and other genes associated with cholesterol biosynthesis were significantly downregulated in Cse −/− mice on the no-Cys diet

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Format Composition: sterile water for injection (USP grade) with 0.9% (w/v) benzyl alcohol preservative Vial sizes: 3 mL and 10 mL multi-dose Container: sealed glass vial with rubber septum suitable for repeated needle puncture Sterility: manufactured under sterile fill conditions