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Mice expressing a stabilized Ctnnb1 transgene phenocopied human aggressive fibromatosis and additionally developed hypertrophic scars after wounding (32), supporting a common mechanism between a genetic fibrosing disorder and trauma-induced cutaneous scarring
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Individual molecules are investigated through different mechanisms—from lipid metabolism in the case of AOD-9604 and mitochondrial signaling in the case of MOTS-c to growth hormone regulation involving Ipamorelin, GHRP-2, Hexarelin, Mod GRF 1-29, and CJC-1295 + DAC