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746 View 34 Download Original Articles Efficacy and safety of ozanimod in Japanese patients with moderately to severely active ulcerative colitis naive to immunomodulators or advanced therapies: post hoc analysis of the phase 2/3 J-True North study Tadakazu Hisamatsu, Toshimitsu Fujii, Hiroshi Nakase, Katsuyoshi Matsuoka, Masayuki Saruta, Taku Kobayashi, Seika Inoue, Kazuhiro Toriyama, Dong Wang, Yoko Uchikawa, Go Fujimoto, Toshifumi Hibi Received January 23, 2026 Accepted May 4, 2026 Published online July 10, 2026 DOI: [Epub ahead of print] Abstract PDFSupplementary MaterialPubReaderePub Background/Aims There is limited evidence for ozanimod, an oral sphingosine 1-phosphate receptor modulator, in patients with ulcerative colitis (UC) before treatment is escalated to an immunomodulator (IM) or advanced therapy (AT), including biologics and Janus kinase inhibitors
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The Role of Peptides in Cellular Function Inside the body, peptides act as molecular signals that tell cells what to do—whether that’s repairing a damaged tendon, supporting energy metabolism, or improving skin structure