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It is worth mentioning miR-155, present in intestinal immune cells, which is responsible for controlling suppressor of cytokine signaling 1 (SOCS1) secretion, which helps maintain IFN-γ expression in NK cells at a constant level, which in turn reduces the activity of the nucleotide-binding domain, leucine-rich–containing family, pyrin domain–containing protein 3 (NLRP3) inflammasome, directly involved in the pathogenesis of UC

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Count:60ct

Severity of Pigmentation: Mild or superficial dullness may respond differently compared to deeper or long-standing hyperpigmentation