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10.1016/j.neures.2021.04.001 289 LiuY.WangY.NiY.CheungC

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found that LPS stimulation led to an approximately 30-fold accumulation of succinate in mouse bone marrow-derived macrophages (BMDMs), which in turn specifically promoted the transcription and expression of IL-1β by inhibiting prolyl hydroxylase (PHD) and stabilizing HIF-1α (25)

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