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A 16-month randomized, placebo-controlled phase II clinical trial evaluated the safety and efficacy of 300, 600, or 1,200 mg/day of coenzyme Q 10 in 80 people with early Parkinson's disease (65)

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IMPDH1 encodes inosine monophosphate dehydrogenase type I, a key enzyme involved in the de novo synthesis of guanine nucleotides, which is essential for the proliferation of T and B lymphocytes