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Another study evaluated neuronal energy metabolism, revealing symptom mitigation, increased immune cell populations (CD4+, CD8+, and CD45+) in the spinal cord, and a reduction in average lesion size in EAE mice [46]

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LXR/CD38 activation drives cholesterol-induced macrophage senescence and… [PMID: 38636518] Laboratory literature summary: LXR/CD38 activation drives cholesterol-induced macrophage senescence and neurodegeneration via NAD(+) depletion

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