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A standard serum B12 test measures both fractions together, so a total result mostly reflects how much haptocorrin is circulating, and haptocorrin is made by white blood cells

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Passing a solution through a validated 0.22-micron membrane under positive pressure removes these organisms with a sterility assurance level (SAL) of 10 to the negative 6, meaning fewer than one in a million units would be expected to contain a viable organism after filtration, per FDA and USP standards for pharmaceutical manufacturing