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The second order rate constant for the first phase depended on the PfGrx variant and was as high as 4.3 × 10 7 M –1 s –1 for roGFP2 WT -PfGrx WT

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Providing the closely interrelated increased pressure in the three body cavities interacting with each other rapidly transmitted through the venous system [28,29] (and thereby, venous system as therapy target [20,21,22,23,24,25,26,27]), the occluded superior sagittal sinus in addition to the brain swelling and lesions and increased pressure in the superior sagittal sinus may induce a comparable deadly syndrome