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in research, Epithalon has been associated with telomere lengthening and reduced mortality in older cohorts, but these findings require more replication and are not guaranteed outcomes

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While tirzepatide established superiority over semaglutide in the SURMOUNT-5 trial—achieving 20.2% weight loss vs 13.7%—indirect network meta-analyses suggest that retatrutide will likely surpass tirzepatide in both absolute and percentage weight reduction