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Oregano plant species have been extensively utilized in traditional medicine to treat inflammation-related disorders via a variety of mechanisms, including Reduced synthesis of proinflammatory cytokines such as TNF-α, IL-1, and IL-6, and increased production of anti-inflammatory cytokines such as IL-10 (206), as well as inhibition of aldose reductase and lipoxygenase (206, 207)

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TB-500 is the synthetic full-length sequence of thymosin β-4, an actin-binding peptide endogenous to most mammalian cell types and originally isolated from calf thymic tissue