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What this does NOT prove: that equivalent BDNF upregulation occurs in human hippocampus at intranasal doses, or that BDNF increases translate to measurable cognitive improvement on validated scales

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For acute injury models (stroke, TBI within 72 hours), Cerebrolysin's multi-pathway neuroprotection outperforms Dihexa's receptor-specific mechanism because it supplies missing growth factors rather than amplifying depleted signaling