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Occasional shock-like sensations that radiate to the thumb and index, middle, and ring fingers Pain or tingling that may travel up the forearm toward the shoulder Weakness and clumsiness in the hand — this may make it difficult to perform fine movements such as buttoning your clothes Dropping things — due to weakness, numbness, or a loss of proprioception (awareness of where your hand is in space) In most cases, the symptoms of carpal tunnel syndrome begin gradually, without a specific injury